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Modern investigations are revealing mechanistic support for some of these approaches in MI/HF models: Preventing ischemia-reperfusion injury: Several TCM metabolites attenuate myocardial ischemia-reperfusion (I/R) injury a key component of MI damage by reducing oxidative stress and cell death

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Direct head-to-head data against tirzepatide showed CagriSema underperforming the highest tirzepatide dose at 84 weeks meaning monotherapy claims of comparable efficacy are not supported by current Phase 3 evidence